Research journal — study summaries & evidence reviews
Plain-language summaries of the clinical trials most often cited in GLP-1 marketing, written to separate what the studies establish from what marketing implies. Every summary describes an FDA-approved product at a studied dose and states explicitly that its results do not transfer to compounded, microdose, or oral formulations. All entries are pending medical review and citation confirmation; specific statistics are not printed as settled until a named reviewer confirms them against the primary source with identifiers.
Pending medical review. The journal publishes summaries in a clearly-labeled provisional state rather than withholding them entirely, so readers can see the evidence framing now. No summary establishes outcomes for any compounded product.
- STEP-UP — semaglutide 7.2 mg (Wegovy HD)
~20.7% at the top dose; cross-trial caveats itemized. Added 2026-08-10 · pending reviewer sign-off. - SURMOUNT-5 — tirzepatide vs semaglutide head-to-head
~20.2% vs ~13.7% at 72 weeks; qualifiers itemized. Added 2026-08-09 · pending reviewer sign-off. - STEP 1: Semaglutide 2.4 mg for Weight Management pending review
The pivotal weight-management trial for the approved injectable product. - SURMOUNT-1: Tirzepatide for Weight Management pending review
The pivotal weight-management trial for the approved tirzepatide product.